Stress is not all bad!
Taking the same pill or power every day for a prolonged or even short term period may cause your body to adjust. I have found this particularly true with Maca and Vit C.
Furthermore, living a completely stress-free life is not the key to an optimal health, stress in the right amount and times can help optimize your overall wellbeing
TED Talk on this very subject:
Article: How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis) - Journal of Experimental Gerontology
http://www.jenage.de/assets/pdfs/library/ristow_zarse_EXPERIMENTAL_GERONTOLOGY_2010.pdf
Upregulation you need to take randomly eg 3 on 3 you’re your body needs the stress?